A significant number of new active pharmaceutical ingredients (APIs) are poorly water soluble and cannot be formulated and processed with traditional aqueous methods. Hot melt extrusion (HME) has become an effective solubilization tool in improving the dissolution rate of poorly water soluble drugs to enhance their bioavailability after oral administration1. These crystalline hydrophobic drugs can be dispersed in hydrophilic polymers using HME to manufacture amorphous solid dispersions.
News & Events
Foster Delivery Science will be speaking and at the 3rd Annual Global Drug Bioavailability Enhancement Summit in Philadelphia July 11-12, 2018!
Join Foster Delivery Science at the Leistritz Pharmaceutical Seminar in Somerville, NJ June 6-7! Tony Listro will represent Foster speaking about the Continuous Twin-Screw Melt Granulation of Thermally Labile Drug Case Study.
March 19 - March 21, 2018